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Science Not yet confirmed elsewhere1 publisher 2 min read Published

Siloton says an £8.4m Innovate UK contract takes one to two years off its retinal imager's time to market

Innovate UK has awarded Siloton £8.4m to develop a portable OCT retinal imager built on a coin-sized chip. The one-to-two-year saving is chief executive Alasdair Price's estimate, and the announced trials cover the in-clinic device.

The Scientist · Science desk

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What happened

  • OCT is the clinical gold standard for retinal disease, but existing systems are large and expensive and sit mostly in hospitals and optometry clinics.
  • Siloton first imaged patients' retinas in 2025 to identify age-related macular degeneration and its progression, and imaged a second cohort earlier this year.
  • The money also supports CheetahOCT, a second-generation research-use device that measures different retinal layers and is due from early 2027.

Why it matters

  • What's now possible capability If a handheld binocular-style device on a coin-sized chip matches hospital scanners, retinal OCT could be used outside hospitals and optometry clinics.
  • What it limits constraint The home version depends on users imaging themselves reliably, and the trials named so far are of the in-clinic device.
  • Who's exposed exposure The hospital trials of the medical-device prototype are still ahead, so the clinical evidence for the product being funded is not yet in.

The one-to-two-year saving is a forecast from the company. "The contract will reduce the time to market for the medical device by one to two years," said Alasdair Price, CEO of Siloton [10]. Physics World's report attributes the estimate to Price alone [10]. The contract itself runs two years [8].

Price also said what the money buys: "It will also allow us to grow the company, bringing in new skills around manufacturing and regulation, both of which are critical to the next stage of the business." [11] Those are the steps between a research-use-only product and a medical device. Price draws that line himself when he describes the planned hospital work: "These trials will be based around the prototype for the full medical device, providing additional post-processing and improved ergonomics compared to our research-use only product line," he said [9].

The evidence so far is mixed in kind. In 2024, using its Akepa chip, Siloton became the first commercial organization to show sub-surface images of a human retina [5]. The Project Ginan consortium in Australia bought a GiraffeOCT research system and evaluated its imaging performance independently, with healthy volunteers [7]. The Ginan evaluation is a useful outside check on image quality. With only healthy eyes, it cannot show whether the device finds disease. The patient imaging for age-related macular degeneration was run by the company itself [6], and the report does not include cohort sizes or a comparison with a hospital OCT scanner.

The home version is the harder claim. The contract covers it, with built-in automation and guidance so that users can reliably image themselves [4]. The trials named in the report, with Sunderland Specialist Eye Hospital, are of the in-clinic device [8]. We would expect the clinic device to reach the market first, since it has a hospital partner and a named prototype, but that is our inference. The only dated product in the report is the research-use CheetahOCT [12].

The chip also does not make the whole instrument small. Price said CheetahOCT "will also be much more compact, as we continue to miniaturize other parts of the system that fall outside the photonic chip" [13].

What to watch

  • Results from the Sunderland Specialist Eye Hospital trials of the in-clinic device, ideally compared against a standard hospital OCT scanner.
  • Any dated plan or regulatory milestone for the at-home version, which the report leaves without a date.
  • Whether CheetahOCT reaches researchers in early 2027 as Siloton says it will.

Clarity's read

What the record supports and how the coverage leans. The claims behind it follow.

Reality

Evidence40
Adoption10
Hype gap+20
Incentives
Not scored
Confidence55
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Claim ledger

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  1. [1]

    Innovate UK awarded UK start-up Siloton an £8.4 million contract to accelerate development of its portable eye imaging system.

    Reported SupportedView cited source
  2. [2]

    OCT is the clinical gold standard for diagnosing retinal diseases, but existing systems are large and expensive and typically only available in hospitals and optometry clinics.

    Reported SupportedView cited source
  3. [3]

    Siloton uses photonic chip technology to shrink bulky optical components onto a single coin-sized chip and is developing an easy-to-use, handheld binocular-style system.

    Reported SupportedView cited source

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Sources

1 independent publisher whose own reporting we read for this story.

  1. physicsworld.com

    1 article · October 16, 2026

    Siloton secures £8.4m to speed development of portable retinal imaging system

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