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Nature Chemical Biology

Peer-reviewed journal in which the bacterial transistor findings were published.

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Control experiment reassigns zavondemstat's main target to DHODH

University of Sydney researchers report that the cancer drug zavondemstat works mainly by blocking the enzyme DHODH, not the KDM4 proteins it was built to hit. The experiments were done in glioblastoma cells, and the drug is already in human trials.

Publishers:medicalxpress.com

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