Research lab
Yale University's medical school, a leading academic center for biomedical research and clinical education.
Yale researchers report that the epilepsy drug lacosamide eased pain and slowed cartilage loss in mouse models and in human cartilage cells in the lab. The work is preclinical, and it still has to be tested in patients with osteoarthritis.
Reality
Yale researchers report that lacosamide, an FDA-approved epilepsy drug, eased joint pain and reversed cartilage damage in preclinical osteoarthritis studies. No FDA-approved medicine yet does both for osteoarthritis, so the open question is whether the effect holds in people.
Reality
The World Health Organization is working with Russian authorities after an employee at a Siberian research institute died of suspected pneumonic plague. Its spokesperson says the cause of death is unconfirmed and testing is still underway.
Reality
A 42-person plasma screen found C3 falling on an 11 to 14 percent calorie cut, and mice supply the causal half. The harms that justify drugging it came from a much deeper diet.
Reality
Aging clocks compress a great deal into one number. A Science study that measured the same 335 women repeatedly over eight years suggests that compression is safer for gene activity than for metabolites, and that when the blood was drawn matters.
Reality
A Yale mouse study in PNAS reports that semaglutide activates AgRP neurons, and that animals lacking those neurons cannot sustain fat loss on the drug.
Reality