Defra has ruled that Tropic Biosciences' non-browning banana, made with edits as small as one DNA letter in three gene copies, is precision bred. That puts it outside England's strict GM food rules, though sales still need a separate Food Standards Agency approval.
Reality
- Evidence62
- Adoption20
- Hype gap+15
- Incentives55
- Confidence55
CTX310, a one-time CRISPR infusion, cut LDL by 52.5% and triglycerides by 47.8% after 12 months at its top dose in a Cleveland Clinic trial. Its 15 patients are enough to show the effect lasts but too few to rule out rare harms or to show it can replace lipid drugs.
Reality
- Evidence55
- Adoption3
- Hype gap+20
- Incentives70
- Confidence60
A Sejong University team knocked out five seed-expressed genes, cutting linoleic and linolenic acid below 1% each and saturated fat by more than 40%. Yield and agronomic stability are still to be evaluated.
Reality
- Evidence62
- Adoption
- Insufficient
- Hype gap+14
- Incentives68
- Confidence58
The Series C values Basecamp Research at about $800 million, roughly 3.6 times everything it has raised, on the strength of a proprietary sequence library and scaling comparisons the company ran internally.
Reality
- Evidence30
- Adoption15
- Hype gap+38
- Incentives78
- Confidence45
Klemens Rottner's group at the Helmholtz Center for Infection Research disrupted lamellipodial proteins singly and in combination, and profilin still directed the Arp2/3 branching complex in cells lacking Ena/VASP. The result picks a side in a long-running dispute.
Reality
- Evidence60
- Adoption
- Insufficient
- Hype gap+28
- Incentives66
- Confidence58
Donor overhangs of about 30 nucleotides, matched to a pair of overhang-complementary pegRNAs, were enough to move exon-sized cargo without a double-strand break. That ceiling is worth knowing even though the public abstract reports no efficiencies.
Reality
- Evidence45
- Adoption
- Insufficient
- Hype gap+15
- Incentives65
- Confidence50
EMBL Heidelberg reports in Nature that T7 phage phosphorylates nearly the whole E. coli proteome within minutes, disabling defence systems that work by different mechanisms.
Reality
- Evidence60
- Adoption
- Insufficient
- Hype gap+18
- Incentives58
- Confidence52
A Dongguk University team reports in Cell that a promoter borrowed from the Lgr4 gene drives expression in mice under a 2.0 millitesla, 60 hertz field, and returns to baseline in 24 hours.
Reality
- Evidence60
- Adoption8
- Hype gap+26
- Incentives52
- Confidence62
AI-designed bacteriophages beat antibiotic-resistant E. coli. New Zealand's gene technology framework is 30 years old, its replacement is stalled in Cabinet, and the design layer sits between regimes.
Reality
- Evidence34
- Adoption21
- Hype gap+22
- Incentives
- Insufficient
- Confidence32
Alfie and Bailey carry a CRISPR knockout of Can f 1 and shed no detectable allergen. The edit was made for human comfort, in animals whose long-term health is unknown.
Reality
- Evidence55
- Adoption5
- Hype gap+10
- Incentives
- Insufficient
- Confidence48
A genome-wide CRISPR screen tied polyamine depletion to GPX4 dependence. A new genetically encoded reporter now puts numbers on redox-active iron inside living cells.
Reality
- Evidence58
- Adoption
- Insufficient
- Hype gap+24
- Incentives55
- Confidence54