Topic

Rheumatoid arthritis

Chronic autoimmune disease in which the immune system attacks the joints, causing recurrent inflammation, swelling and eventual joint damage.

Current clusters

science1 publisher

Semmelweis researchers want depression and sleep checked before rheumatoid arthritis drugs are escalated

Semmelweis researchers say depression, poor sleep, obesity and smoking may sustain symptoms in the 6-28% of rheumatoid arthritis cases that resist treatment. They want doctors to look for those causes before escalating drugs when inflammation markers improve but pain and fatigue persist.

Publishers:sciencedaily.com

Reality

Evidence45
Adoption30
Hype gap+25
Incentives55
Confidence50

science2 publishers

A single CD19 CAR-T infusion held three of six refractory rheumatoid arthritis patients drug-free

The Berlin phase 1 trial was built to measure cytokine release syndrome rather than remission, and its six-patient denominator carries no comparator, so the ten-patient second phase against an approved B-cell drug is the one that settles anything.

Publishers:genengnews.comsciencedaily.com

Reality

Evidence35
Adoption: Insufficient
Hype gap+30
Incentives40
Confidence60