Topic

Major depressive disorder biology

Mechanistic accounts of clinical depression beyond the serotonin-deficiency model, including subtype heterogeneity.

Current clusters

science1 publisher

Helsinki MEG recordings sort 263 depression patients into five connectivity profiles

Magnetoencephalography in 263 patients and 75 controls yielded five connectivity groups, one with widespread reductions in coupling and one with the strongest coupling in the study, each tracking a different symptom mix.

Publishers:neurosciencenews.com

Reality

Evidence42
Adoption5
Hype gap+33
Incentives62
Confidence46

science2 publishers

Columbia says depression stalls new neurons. The subtype it implies has no test yet

The first human evidence for the neurogenesis hypothesis arrives with a hedge from the lead author and no described way to measure the marker in a living patient.

Publishers:nature.comsciencedaily.com

Reality

Evidence57
Adoption10
Hype gap+38
Incentives62
Confidence68