Weill Cornell-led researchers found 18% of under-65 patients had cognitive impairment within two years of neck lymph node removal, versus 4-6% expected. Because the comparison is with population rates, the finding makes a firmer case for cognitive follow-up than for cutting less.
Reality
- Evidence55
- Adoption
- Insufficient
- Hype gap+35
- Incentives35
- Confidence50
Weill Cornell biophysicists used cryo-EM to map the pocket where trace amounts of the lipid PIP2 dock onto rod-cell CNG channels and hold them shut. The site is a candidate drug target for inherited retinal degeneration, so far studied only in synthetic membranes.
Reality
- Evidence55
- Adoption
- Insufficient
- Hype gap+35
- Incentives35
- Confidence50
Seventy percent of American adults say they are more worried than excited about AI, and the one exception in the polling is scientific research and medicine. The fastest uptake inside medicine is administrative.
Reality
- Evidence42
- Adoption32
- Hype gap+18
- Incentives38
- Confidence45
Two Nature Communications papers describe mGluR receptors binding beta-arrestins in varying numbers and orientations. The authors say that variety, plus a first structure of an active complex, points to why earlier drugs disappointed.
Reality
- Evidence58
- Adoption
- Insufficient
- Hype gap+25
- Incentives62
- Confidence55
A Nature Communications model from Weill Cornell argues that a target protein's turnover rate can matter as much as how tightly a degrader binds it, which would reorder where degrader programs spend their optimisation money.
Reality
- Evidence32
- Adoption
- Insufficient
- Hype gap+38
- Incentives72
- Confidence45
A Nature paper reports promoter and CRISPR toolsets that transfer across distantly related gut Clostridia, then uses them to toggle two host-relevant metabolites in mice. The methods stay paywalled.
Reality
- Evidence60
- Adoption15
- Hype gap+18
- Incentives58
- Confidence62
Cornell researchers identified the species of 1.8 million NYC trees at 82% accuracy, including the two-thirds of canopy nobody had surveyed. Planting targets now have to name names.
Reality
- Evidence64
- Adoption20
- Hype gap+22
- Incentives68
- Confidence58