other

SLIM LIVER trial

Human trial whose recent post-hoc analysis GEN cites as an example of the clinical evidence needed on GLP-1s and longevity.

Known aliases

SLIM LIVER

Relationships

No evidence-backed relationships are recorded.

Current clusters

science1 publisher

Semaglutide added nearly 100 days to the median lifespan of 20-month-old mice

An NIH-funded UC Berkeley team dosed old, healthy female mice, then fed a second group 24% fewer calories to match what the drug's appetite suppression achieved. The drug still did more on memory and blood sugar.

Publishers:sciencedaily.com

Reality

Evidence62
Adoption: Insufficient
Hype gap+22
Incentives58
Confidence55

science3 publishers

Semaglutide started in old age added 92 days to female mice's median lifespan

A Berkeley group ran the drug against a matched 24 percent food cut and found it equalled dieting on strength and coordination while beating it on memory and glucose. The lifespan race between the two is still running.

Publishers:genengnews.comnature.comscientificamerican.com

Perspective Coverage

3 publishers

Builder: Builder 44%
Operator: Operator 33%
Investor: Investor 23%

Reality

Evidence74
Adoption28
Hype gap+16
Incentives42
Confidence68