The Allen Institute, the University of Washington and Fred Hutchinson are building models and databases of designed proteins. David Baker told WIRED the field usually sees that something works before it knows why.
Reality
- Evidence34
- Adoption
- Insufficient
- Hype gap+45
- Incentives66
- Confidence52
A University of Washington and Fred Hutch autopsy programme sequenced tumours from 20 people who died of bladder cancer to reconstruct how the disease spread. Plasmacytoid tumours turned out to limit the genomic damage chemotherapy leaves behind.
Reality
- Evidence74
- Adoption
- Insufficient
- Hype gap+8
- Incentives55
- Confidence66
Revolution Medicines' expanded access program for Rasonque closed immediately on FDA approval, leaving patients still mid-application to wait on insurers whose paperwork moves slower than metastatic pancreatic cancer.
Reality
- Evidence62
- Adoption45
- Hype gap+12
- Incentives55
- Confidence60
Twenty-six risk regions, about half of them near genes for nerve cell growth and pain sensitivity, give the condition the biological footing that decades of clinical dismissal lacked, though none of them can diagnose a patient.
Reality
- Evidence62
- Adoption8
- Hype gap+12
- Incentives45
- Confidence56
Cornell researchers say single-cell sequencing separates a destructive benign canine oral tumor from its malignant lookalike, and that an ERBB4 inhibitor slowed it in live tissue.
Reality
- Evidence42
- Adoption
- Insufficient
- Hype gap+38
- Incentives64
- Confidence34