science1 publisher
Directed evolution shrinks the red-light optogenetic switch to 23 kilodaltons
Researchers report FenixS, a 17-kDa monomeric biliverdin-binding photoreceptor, and Ash1, a 6-kDa binder whose affinity for it rises more than 1,200-fold under 700-nm light in mammalian cells with no added cofactor.
Publishers:nature.com
Reality
- Evidence52
- Adoption8
- Hype gap+14
- Incentives45
- Confidence55