Topic

Dual photoredox-nickel catalysis

Cross-coupling in which a photocatalyst generates a carbon radical under visible light and a nickel catalyst joins it to an organic halide, allowing sp3 partners that classical palladium coupling handles poorly.

Current clusters

science1 publisher

Borane coordination opens the N-alkyl aziridines that metal catalysis leaves inert

Peng and colleagues coordinate BH3 to an aziridine nitrogen, convert the adduct into a boryl radical, and let it fragment into a beta-aminoalkyl radical that copper and nickel catalysis can then couple to aryl and other partners.

Publishers:nature.com

Reality

Evidence60
Adoption: Insufficient
Hype gap+12
Incentives60
Confidence57