science1 publisher
Tris storage buffer keeps mRNA nanoparticles potent through freezing
UT Austin, Eli Lilly and Boston University found a Tris buffer keeps mRNA nanoparticles potent through freezing, where citrate cannot. Only 5% to 10% of an mRNA dose reaches its target, so the storage solution shapes how much material a patient needs.
Publishers:phys.org
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