Topic

Molecular self-assembly

The process by which molecular components spontaneously organise into ordered structures such as protein shells, filaments and compartments, without a template or external machinery directing them.

Current clusters

science1 publisher

Shih's lab standardizes the design of crisscross DNA megastructures in software

William Shih's group at the Wyss Institute and Dana-Farber has published a computational framework in Nature Communications for crisscross DNA megastructures, aimed at the unwanted-binding problem Shih says keeps the method in a few labs.

Publishers:phys.org

Reality

Evidence58
Adoption10
Hype gap+30
Incentives70
Confidence45

science1 publisher

Oxford weighed individual virus-like particles as they assembled, one subunit at a time

By holding single molecules still and weighing them over and over, an Oxford team recorded each protein subunit joining a 60-unit shell. The traces put the first stable structure at a closed ring of five.

Publishers:phys.org

Reality

Evidence68
Adoption: Insufficient
Hype gap+14
Incentives55
Confidence62