Topic

Genetic ancestry as a continuum

The practice of treating human genetic ancestry as continuous variation, usually summarised by principal components or admixture proportions, instead of sorting people into discrete population categories.

Current clusters

science1 publisher

A label-free polygenic score improved prediction for non-European and admixed biobank participants

SPLENDID fits one penalized regression that treats genetic ancestry as a continuum, and its authors report more accurate prediction in All of Us and UK Biobank than methods that first sort people into ancestry groups.

Publishers:nature.com

Reality

Evidence55
Adoption12
Hype gap+25
Incentives40
Confidence50