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DNA replication

The copying of a cell's genome before division, carried out by enzyme machinery that travels along each DNA strand to produce two identical copies of every chromosome.

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Cohesin reorganizes newly copied DNA where replication stalls

A Nature paper from the University of Zurich and the CNIO reports that cohesin is pulled to sites where DNA replication is disrupted, holds the new copy in a protective arrangement, and keeps the error-prone restart factor Primpol switched off.

Publishers:phys.org

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