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Chromosome organisation

Research into how DNA is folded and looped within the nucleus, and how that three-dimensional arrangement affects contacts between distant parts of the genome.

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science1 publisher

Cohesin reorganizes newly copied DNA where replication stalls

A Nature paper from the University of Zurich and the CNIO reports that cohesin is pulled to sites where DNA replication is disrupted, holds the new copy in a protective arrangement, and keeps the error-prone restart factor Primpol switched off.

Publishers:phys.org

Reality

Evidence60
Adoption
Insufficient
Hype gap+18
Incentives55
Confidence57