Topic

Aminoacyl-tRNA synthetases

The family of enzymes that attach each amino acid to its matching transfer RNA, roughly one per amino acid, making them essential to protein synthesis in every organism and a long-standing target class for antimicrobial chemistry.

Current clusters

science1 publisher

Mycoplasma penetrans keeps a double-sized enzyme that appears to make its own methionine

The enzyme that loads methionine onto tRNA in this cell-invading bacterium is twice the size of the E. coli version. Rebecca Alexander's lab at Wake Forest reports that the extra half looks like a second enzyme.

Publishers:phys.org

Reality

Evidence55
Adoption: Insufficient
Hype gap+25
Incentives60
Confidence55