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Science1 publisher2 min readPublished

Exercise keeps 14 astronauts' hearts within Mars-tolerable range, station echocardiograms show

A Circulation study co-led by UT Southwestern measured astronaut hearts during six-month station missions, the window earlier work left blank, and reports the early shrinkage stayed inside what Mars-level gravity would demand.

The Scientist · Science desk

Photograph accompanying Exercise keeps 14 astronauts' hearts within Mars-tolerable range, station echocardiograms show
Photo: utsouthwestern.edu

What happened

  • NASA's Integrated Cardiovascular Study, which set out to define cardiac risks and guide countermeasures for future missions, published a phase in Circulation asking how the heart remodels during a long flight.
  • The cohort was 14 astronauts, nine male and five female, each aboard the International Space Station for about six months, close to the duration of a flight to Mars.
  • Cardiac MRI cannot be used in flight, so the team measured the heart's anatomy and pumping efficiency with echocardiography and Doppler, run in orbit by crewmates trained on the equipment.
  • Every astronaut had some change in heart structure and function in the first two weeks, with slight shrinkage, and the phys.org account reports those early changes reversed.

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Why it matters

  • capability Before this, the study had heart measurements from before and after a mission and nothing from inside it, so countermeasure policy can now be argued from a time course instead of two endpoints.
  • decision If the routine already flying is sufficient for Mars-level loads, the planning question for a transit becomes protecting that daily hour of crew time and the hardware that supports it.
  • constraint With everyone on the same program, the results cannot say what a shorter routine would do, so a proposal to trade exercise time for other tasks gets no support here.
  • exposure The Mars-level reference in the protocol was taken on the ground before launch. The case for working in 0.375 g after six months of weightlessness rests on that preflight tilt.

All fourteen astronauts exercised. Each began the station's standard routine as soon as they were able, roughly 45 minutes to an hour a day of endurance and strength work [14]. There is no unexercised group in the study [26], so the untreated comparison is the older literature. "Our previous studies had demonstrated that the heart atrophies in both bed rest and in space," said Benjamin Levine, professor of internal medicine in UT Southwestern's Division of Cardiology [3][4].

Taken across about 180 days, 45 to 60 minutes daily comes to roughly 135 to 180 hours of exercise per crew member [21]. The routine was the programming already standard on the International Space Station [14].

Before launch, each astronaut was scanned in three positions: lying flat for zero gravity, at a 22% tilt for something close to Mars, and sitting upright for Earth [11]. Mars' gravity is about 3/8 of Earth's [13], or about 0.375 g [20].

In orbit the scans came at about days 14, 30, 75 and 135, then once more 15 days before landing [12]. Five sessions, three of them inside the first 75 days [23]. On a roughly 180-day mission the last one falls near day 165, about a month after the day-135 scan [22].

Levine said the early change was not surprising, because most astronauts experience some motion sickness [16]. The paper does not report the electrical activity the Integrated Cardiovascular Study also set out to characterize [5]; echocardiography with Doppler measured the heart's anatomy and how efficiently it pumped blood [9].

Levine worked on this phase with Michael Bungo of the McGovern Medical School at UTHealth Houston and James Thomas of the Northwestern University Feinberg School of Medicine [6]. "Our findings suggest that the exercise countermeasures we already have in place are enough to keep the heart in good working order for Mars' gravitational loads," Levine said [2].

What to watch

  • Magnitudes from the Circulation paper itself: how much size and pumping function the hearts lost, and how far they came back.
  • Whether NASA extends the same scanning protocol past six months, where the gap between the day-135 scan and landing widens.
  • Whether echo-derived remodeling numbers can be reconciled with the MRI-based bed-rest atrophy measurements that raised the concern.
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