Florian Naudet's team re-ran two Prozac meta-analyses without one 2006 trial of 40 Iranian children, and the drug's large edge in child depression vanished. The authors want guideline committees to re-weigh Prozac's recommendation but are not asking doctors to stop prescribing.
Reality
- Evidence70
- Adoption
- Insufficient
- Hype gap+5
- Incentives
- Insufficient
- Confidence65
Eli Lilly's retatrutide cut body weight by more than 20% on average at its top dose in an 80-week phase 3 trial of 1,152 people with type 2 diabetes. Lilly calls that a first for the field, and it gives the four- and five-receptor drugs now in development a figure to beat in patients with diabetes.
Reality
- Evidence68
- Adoption
- Insufficient
- Hype gap+12
- Incentives72
- Confidence62
Sustentarea at the University of Sao Paulo mapped under-5 stunting and overweight against per capita emissions for Brazilian municipalities from 2008 to 2019. It shows where the problems overlap, though local emissions cannot test the climate-to-diet chain said to link them.
Reality
- Evidence55
- Adoption
- Insufficient
- Hype gap+15
- Incentives
- Insufficient
- Confidence50
The World Health Summit Academic Alliance and The Lancet have seated 30 commissioners from 22 countries to work out how academic institutions should be designed and governed, with recommendations due in 2028.
Reality
- Evidence38
- Adoption15
- Hype gap+35
- Incentives72
- Confidence55
The ISGlobal-led study puts avertable deaths at 6.6 to 29.5 million by 2030, and that four-and-a-half-fold spread turns on which tax is levied and at what rate rather than on any statistical bound.
Reality
- Evidence45
- Adoption
- Insufficient
- Hype gap+32
- Incentives58
- Confidence52
A new WHO burden estimate covering 14 parasitic diseases finds nematodes alone caused 143 million foodborne cases, with two disease groups accounting for nearly the whole total.
Reality
- Evidence64
- Adoption
- Insufficient
- Hype gap+8
- Incentives30
- Confidence55