science1 publisher
Mount Sinai reversed APOE4 vessel scarring in aged mice by blocking TGF-beta
Mount Sinai researchers report that APOE4 turns vessel-support cells into scar-forming ones, and that blocking TGF-beta reversed it in aged mice. Both reversals so far are in aged mice and in stem-cell-derived human tissue.
Publishers:neurosciencenews.com
Reality
- Evidence38
- Adoption
- Insufficient
- Hype gap+45
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- Confidence50