other

SFPQ

Splicing factor proline- and glutamine-rich, a multifunctional nuclear RNA-binding protein studied in splicing, transcriptional elongation and neurodegeneration.

Known aliases

splicing factor proline- and glutamine-rich

Relationships

No evidence-backed relationships are recorded.

Current clusters

science2 publishers

SFPQ condensates keep neurons' two-megabase genes transcribing to the end

An Ehime University team reports that SFPQ binds newly made RNA and uses it to build nuclear compartments where elongation, splicing and chromatin remodeling proceed together. Its autism and ALS link rests on overlapping gene lists.

Publishers:neurosciencenews.comphys.org

Reality

Evidence62
Adoption: Insufficient
Hype gap+30
Incentives48
Confidence58