science1 publisher
Removing NUDT5 made cells resistant to a 70-year-old leukemia drug
CeMM and Oxford researchers degraded the protein NUDT5 in cells and made them resistant to 6-thioguanine, while inhibiting the same enzyme had little effect. The split separates what the protein catalyses from what it does by being present.
Publishers:sciencedaily.com
Reality
- Evidence42
- Adoption
- Insufficient
- Hype gap+10
- Incentives68
- Confidence60