science1 distinct publisher
Donor-complementary prime editing carries 12.5 kilobases into the genome in a single step
Donor overhangs of about 30 nucleotides, matched to a pair of overhang-complementary pegRNAs, were enough to move exon-sized cargo without a double-strand break. That ceiling is worth knowing even though the public abstract reports no efficiencies.
Publishers:nature.com
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