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Vaccine adjuvants and trained immunity — Clarity Today

Topic

Vaccine adjuvants and trained immunity

Hypotheses that the AS01 adjuvant reprogrammes monocytes and dampens inflammatory cytokine responses.

Current clusters

science2 distinct publishers

Oxford's Zostavax-to-Shingrix switch closes the healthy-vaccinee loophole, and opens another

A natural experiment at the October 2017 vaccine changeover gives the cardiovascular claim a cleaner comparison group. It also means nobody has yet measured Shingrix against no vaccine.

Publishers:newscientist.com · statnews.com

Reality

Evidence63
Adoption58
Hype gap+20
Incentives42

Confidence74