Topic

Tumour evolution and metastasis

Research into how tumours accumulate mutations, branch into clones and seed new sites over the course of a disease, often reconstructed as a phylogeny from multiple sampled lesions.

Current clusters

science1 publisher

Twenty rapid autopsies show bladder cancer metastases mostly seeding other metastases

A University of Washington and Fred Hutch autopsy programme sequenced tumours from 20 people who died of bladder cancer to reconstruct how the disease spread. Plasmacytoid tumours turned out to limit the genomic damage chemotherapy leaves behind.

Publishers:nature.com

Reality

Evidence74
Adoption: Insufficient
Hype gap+8
Incentives55
Confidence66