science1 publisher
Structure search for CRISPR's ancestor turns up a viral protein that opens DNA with a triplex
Two Science papers name the protein VIPR and show it silencing a reporter gene and blocking phage in E. coli, guided by an RNA that reads two DNA letters and skips the third, a targeting rule anyone borrowing it will have to design around.
Publishers:phys.org
Reality
- Evidence62
- Adoption10
- Hype gap+30
- Incentives50
- Confidence58