Topic

Protein language models

Machine-learning models that encode protein amino acid sequences, and sometimes three-dimensional structures, as numerical embeddings for search, classification and design.

Current clusters

science1 publisher

Contrastive training lands a protein's sequence and its structure in the same spot on the map

Reported in PNAS, the CLSS model reproduces relationships from the expert-curated ECOD and CATH classifications it never saw in training, and it can place short protein fragments beside complete sequences and structures.

Publishers:phys.org

Reality

Evidence52
Adoption: Insufficient
Hype gap+20
Incentives58
Confidence55