Topic

Early-phase oncology trials

First-in-human cancer studies that test dose, safety and early signs of activity in small groups of patients, usually without a randomised control arm.

Current clusters

science1 publisher

Blocking the antioxidant enzyme PRX3 controlled disease in 67% of an early mesothelioma trial

Years of cancer trials that boosted antioxidants failed, so a University of Vermont team tried stripping mesothelioma cells of one antioxidant enzyme instead, and an early-phase trial reports disease control in two-thirds of patients.

Publishers:sciencedaily.com

Reality

Evidence45
Adoption15
Hype gap+35
Incentives78
Confidence50