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Topic

DNA repair

The cellular processes that detect and fix damage to DNA, including homologous recombination, whose failure is linked to cancer and inherited disorders.

Current clusters

science1 publisher

Crick structures show how RAD51 paralogs build and cap DNA repair filaments

Crick researchers report that two four-subunit RAD51 paralog complexes assemble and cap DNA repair filaments, after about 20 years of stalled study. The genes sit in the BRCA pathway and the structures may help explain disease mutations, but the work includes no drug or patient data.

Publishers:phys.org

Reality

Evidence50
Adoption
Insufficient
Hype gap+10
Incentives40
Confidence55