Topic

Fitness costs of resistance

The idea that mutations letting bacteria survive a drug can also make them slower-growing or less able to cause disease, a trade-off researchers try to exploit therapeutically.

Current clusters

science1 publisher

Umeå team blocks MRSA's evolutionary route back to beta-lactam resistance

A Nature Communications study from Umeå University reports that stressing the lipid carrier bacteria use to build their cell wall stopped MRSA from evolving its way back to resistance. The paper's title names statins as the stressor.

Publishers:phys.org

Reality

Evidence52
Adoption: Insufficient
Hype gap+18
Incentives62
Confidence58