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RAD51 paralogs

A family of human DNA repair proteins related to RAD51, including RAD51B, RAD51C, RAD51D, XRCC2 and XRCC3, that act in homologous recombination.

Known aliases

  • XRCC3-RAD51C-RAD51D-XRCC2

Relationships

No evidence-backed relationships are recorded.

Current clusters

science1 publisher

Crick structures show how RAD51 paralogs build and cap DNA repair filaments

Crick researchers report that two four-subunit RAD51 paralog complexes assemble and cap DNA repair filaments, after about 20 years of stalled study. The genes sit in the BRCA pathway and the structures may help explain disease mutations, but the work includes no drug or patient data.

Publishers:phys.org

Reality

Evidence50
Adoption
Insufficient
Hype gap+10
Incentives40
Confidence55