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Fanconi anemia

Rare inherited disorder of DNA repair that causes bone marrow failure and raises cancer risk.

Known aliases

  • Fanconi anaemia

Relationships

No evidence-backed relationships are recorded.

Current clusters

science1 publisher

Crick structures show how RAD51 paralogs build and cap DNA repair filaments

Crick researchers report that two four-subunit RAD51 paralog complexes assemble and cap DNA repair filaments, after about 20 years of stalled study. The genes sit in the BRCA pathway and the structures may help explain disease mutations, but the work includes no drug or patient data.

Publishers:phys.org

Reality

Evidence50
Adoption
Insufficient
Hype gap+10
Incentives40
Confidence55