science1 publisher
Ben-Gurion researchers trace a redox switch that tips stressed human cells into apoptosis
Ben-Gurion University researchers say disulfide bonds in two ER chaperones, DNAJB12 and DNAJB14, decide whether stressed human cells survive or self-destruct. The evidence comes from cultured human cell lines, so using the pair against chemotherapy-resistant tumours is still a hypothesis to test.
Publishers:phys.org
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