standard

ACMG/AMP variant classification criteria

Joint framework from the American College of Medical Genetics and Genomics and the Association for Molecular Pathology for classifying sequence variants by pathogenicity, combining evidence categories, population frequency thresholds and computational predictions.

Known aliases

ACMG/AMP

Relationships

No evidence-backed relationships are recorded.

Current clusters

build1 publisher

AWS measures its 38 healthcare agent skills against the same agents without them

The collection encodes ACMG/AMP criteria and GATK4 parameters as markdown that loads on a trigger. The 70 to 86 percent figure AWS publishes comes from head-to-head comparisons with its own unskilled agents.

Publishers:aws.amazon.com

Reality

Evidence35
Adoption15
Hype gap+30
Incentives80
Confidence60